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Semaglutide

Why Semaglutide?

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Semaglutide versus other GLP-1 medications:

Compared to other GLP-1 receptor agonists, semaglutide has shown superior efficacy in glycemic control and weight loss. Its long-acting formulation allows for once-weekly dosing, providing greater convenience for patients.

How Semaglutide works:

Semaglutide functions by mimicking the natural hormone GLP-1. It enhances insulin secretion, reduces glucagon release, and slows the emptying of the stomach. These actions help lower blood glucose levels and support weight loss.

How to take Semaglutide:

Semaglutide is given as a subcutaneous injection, usually once a week on the same day each week, using a prefilled pen. It can be administered at any time of day, with or without food.

Weekly dosing schedule:

  • First four weeks: Start with a dose of 0.25 mg once a week.
  • Second four weeks: Increase the dose to 0.5 mg once a week.
  • Third four weeks: The dose can be further increased to 1.0 mg once a week if needed.
  • Fourth week and continuing dosage: The maximum dose of semaglutide is 2.4 mg once a week for weight management and 1.0 mg once a week for type 2 diabetes management.

Weight loss benefits by taking Semaglutide:

Semaglutide has been proven to support significant weight loss in individuals with obesity and type 2 diabetes. Clinical studies have shown an average weight reduction of approximately 5–10% of initial body weight, with some patients achieving even greater results. This weight loss is mainly attributed to decreased appetite and enhanced feelings of fullness, resulting in reduced calorie consumption.

How often should you do a blood draw for testing for side effects? Every four weeks?

The frequency of blood tests while taking semaglutide depends on each person’s unique medical condition. Regular monitoring of blood glucose levels and kidney function is advised, particularly during the early weeks of treatment. Your healthcare provider will determine how often tests are needed based on your medical history and how you respond to the medication.

How often should you do a blood draw for testing for side effects? Every four weeks?

Some common side effects of semaglutide include:
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Decreased appetite.
  • Headache
  • Dizziness
  • Fatigue
  • Injection site reactions

Rare but serious side effects may include:

  • Pancreatitis
  • Thyroid C-cell tumors
  • Severe allergic reactions

How to address the Semaglutide side effects using functional medicine support, including supplements and IV Drips:

To manage side effects from semaglutide, consider the following functional medicine approaches:  

  • Hydration: Ensuring adequate fluid intake can help alleviate gastrointestinal side effects like nausea, vomiting, and diarrhea.
  • Ginger: Ginger supplements or tea may help reduce nausea.
  • Probiotics: Probiotic supplements can help restore gut balance and alleviate gastrointestinal side effects.
  • Slow dose escalation: Gradually increasing the dose of semaglutide, as recommended by your healthcare provider, can help reduce the severity of side effects as the body adjusts to the medication.
  • Dietary adjustments: Eating smaller, more frequent meals and avoiding high-fat or spicy foods can help manage gastrointestinal side effects.
  • Electrolyte supplementation: Replenishing electrolytes, particularly if experiencing diarrhea or vomiting, can help maintain proper electrolyte balance.
  • Vitamin and mineral supplementation: Some individuals may benefit from vitamin and mineral supplementation to ensure adequate nutrient intake, especially if appetite is reduced.
  • Stress management: Engaging in stress-reducing activities such as meditation, deep breathing exercises, or yoga can help manage stress, which may exacerbate side effects.
  • Sleep optimization: Prioritizing sleep and establishing a healthy sleep routine can help promote overall well-being and potentially reduce side effects.
  • IV Drips: In some cases, IV therapy may be used to replenish fluids, electrolytes, and essential nutrients lost due to gastrointestinal side effects. Consult with a healthcare professional before considering IV therapy.
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